Staffordshire, United Kingdom

Kai S Lipinski


Average Co-Inventor Count = 3.3

ph-index = 1

Forward Citations = 4(Granted Patents)


Company Filing History:


Years Active: 2003-2015

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3 patents (USPTO):Explore Patents

Title: Innovator in Genetic Engineering: The Contributions of Kai S Lipinski

Introduction

Kai S Lipinski, an accomplished inventor based in Staffordshire, GB, has made significant contributions to the field of genetic engineering. With three patented inventions to her name, she continues to push the boundaries of scientific understanding and application in gene expression.

Latest Patents

Among her latest patents, one notable invention focuses on "Expression Elements." This invention relates to improved genetic elements that enable high levels of expression of operably-linked genes across various tissues. It specifically showcases fragments of unmethylated CpG islands of less than 2 kb that enhance transgene expression and offer advantages concerning vector construction and cloning capacity.

Another significant patent from Lipinski involves "Gene Expression Using T Cell Factor Responsive Element." This disclosure features DNA elements and constructs that facilitate tumor-selective gene expression in tumors with a mutated β-catenin/APC pathway. The constructs incorporate multiple repeats of a TCF-binding element that is operably linked to a promoter, allowing for tumor cell-specific expression of therapeutic proteins. This can lead to selective killing of colorectal cancer cells when coupled with a suitable prodrug, such as CB1954.

Career Highlights

Throughout her career, Kai S Lipinski has worked with notable companies, including M. L. Laboratories Plc and Innovata Limited. Her expertise in genetic engineering and patenting has allowed her to contribute to several advancements that could revolutionize cancer treatment and gene therapy.

Collaborations

Lipinski has collaborated with esteemed colleagues such as Lawrence S Young and Christopher J Wrighton. Together, they have contributed to various projects aimed at improving therapeutic strategies in oncology through innovative gene expression methods.

Conclusion

Kai S Lipinski’s innovative work in genetic engineering illustrates the profound impact that patents can have on advancing medical science. With her ongoing contributions and collaborations, she continues to inspire future inventions that may lead to groundbreaking treatments for complex diseases.

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