Juzheng Sheng

Title: Juzheng Sheng: Innovator in Heparin Skeleton Synthase

Introduction

Juzheng Sheng is a notable inventor based in Jinan, China. He has made significant contributions to the field of biochemistry, particularly in the development of heparin skeleton synthase and its mutants. His innovative work has implications for various applications in biotechnology.

Latest Patents

Juzheng Sheng holds a patent for "Heparin skeleton synthase and its mutants and application." This patent describes a heparin skeleton synthase that originates from a specific amino acid sequence, as shown in SEQ ID NO.2, and a nucleotide sequence of the coding gene, as shown in SEQ ID NO.1. The recombinant expression level of this synthase is 6.8 times that of the existing heparin skeleton synthase KfiA from K5. Additionally, the total enzyme activity per fermentation liquor is 5.22 times that of KfiA. The mutants obtained through site-directed mutagenesis at specific sites in the amino acid sequence exhibit high expression levels.

Career Highlights

Throughout his career, Juzheng Sheng has worked with esteemed institutions such as Shandong University and Bloomage Biotechnology Corporation Limited. His research and innovations have contributed to advancements in the field of biotechnology.

Collaborations

Juzheng Sheng has collaborated with notable colleagues, including Xueping Guo and Jianqun Deng. Their combined efforts have furthered research in the area of heparin synthase.

Conclusion

Juzheng Sheng's contributions to the field of biochemistry, particularly through his patent on heparin skeleton synthase, highlight his role as an innovator. His work continues to influence advancements in biotechnology and related fields.