Company Filing History:
Years Active: 1989
Title: Junichiro Asaka: Innovator in Genetic Engineering
Introduction
Junichiro Asaka is a prominent inventor based in Sakai, Japan. He has made significant contributions to the field of genetic engineering, particularly in the development of innovative methods for manipulating bacterial motility through genetic modifications.
Latest Patents
Asaka holds a patent for "DNA encoding flagellin and vector having the same." This invention involves the determination of the whole DNA sequence coding for flagellin of E. coli (hag gene) cloned in phage λ. The hag gene is introduced into pBR322, with the region concerning the antigenicity of flagella lacking, into which linkers are inserted. When the vector containing foreign DNA is introduced into E. coli that does not form flagella, the bacteria can then produce flagella and exhibit motility. The flagella consist of flagellin fused with a foreign peptide encoded by the foreign DNA, allowing the foreign peptide to be excreted outside of the bacteria. This system can be utilized for the determination of epitopes, preparation of antigens, and excretion of peptides.
Career Highlights
Junichiro Asaka is associated with Shionogi Company Limited, where he continues to advance his research and innovations in genetic engineering. His work has implications for various applications in biotechnology and medicine.
Collaborations
Asaka has collaborated with notable colleagues, including Tamio Fujiwara and Takashi Fujiwara, contributing to the advancement of their shared research interests.
Conclusion
Junichiro Asaka's innovative work in genetic engineering, particularly his patent on DNA encoding flagellin, showcases his significant contributions to the field. His research continues to pave the way for advancements in biotechnology and medical applications.