This inventor holds 2 USPTO granted patents. Top assignee: University of Massachusetts. Active years: 2017-2018.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Company Filing History:
Years Active: 2017-2018
Title: Jun Jiang and Chromosome 21 Dosage Compensation
Introduction
Jun Jiang is an inventor associated with Shrewsbury, Massachusetts, and the University of Massachusetts. His patent work concerns genetic approaches to reducing the expression of genes on Chromosome 21.
Latest Patents
Jiang is associated with 2 patents. His listed patent, “Dosage Compensating Transgenes and Cells,” describes methods and compositions for reducing the expression of genes on Chromosome 21 by targeting an XIST transgene to either the DYRK1A or RCAN1 gene. The disclosed work also covers cells and transgenic animals with an XIST transgene inserted into a DYRK1A or RCAN1 allele, including models trisomic for human Chromosome 21 or mouse Chromosome 16.
Career Highlights
Jiang’s patent activity reflects research into gene dosage and chromosome biology. The described approach uses an XIST transgene to investigate ways of compensating for the increased gene expression associated with an extra copy of Chromosome 21.
Collaborations
Jiang’s listed coworkers include Jeanne B. Lawrence and Lisa L. Hall. His work is associated with the University of Massachusetts.
Conclusion
Jun Jiang’s patent work focuses on XIST-based strategies for reducing the expression of selected Chromosome 21 genes, connecting his research with broader efforts to study dosage compensation and trisomy.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile