Company Filing History:
3 out of 4 
3 out of 949 
1 out of 167 
Years Active: 2005-2012
Title: Jun-Ichi Yamamoto: Innovator in Smooth Muscle Cell Research
Introduction
Jun-Ichi Yamamoto is a notable inventor based in Chiba, Japan. He has made significant contributions to the field of biotechnology, particularly in the study of smooth muscle cell differentiation. With a total of 7 patents to his name, his work has implications for drug development and understanding cellular processes.
Latest Patents
One of his latest patents involves an antibody directed to a protein that plays a crucial role in maintaining the differentiation of smooth muscle cells. This invention was developed through isolating a cDNA fragment using a culture system of chicken gizzard smooth muscle cells, employing differential display and subtracted hybridization methods. The resulting cDNA sequence led to the identification of a novel gene, 'C-NT2RP3001495', which encodes a protein with two WW domains that are essential for protein interactions. This protein is believed to regulate intracellular signal transduction and gene expression, making it valuable for developing drugs targeting diseases related to smooth muscle cell differentiation abnormalities.
Another significant patent is related to the full-length cDNA and polypeptides derived from human sources. This invention provides complete nucleotide sequences and amino acid sequences, which are crucial for analyzing the functions of the polypeptide. The full-length nature of the cDNA ensures that it contains the translation start site, enhancing its utility in research.
Career Highlights
Throughout his career, Jun-Ichi Yamamoto has worked with prominent organizations, including the Research Association for Biotechnology and Chugai Pharmaceutical Co., Ltd. His research has been instrumental in advancing our understanding of smooth muscle cell biology and its applications in medicine.
Collaborations
He has collaborated with notable colleagues such as Takao Isogai and Tomoyasu Sugiyama, contributing to a rich exchange of ideas and innovations in their field.
Conclusion
Jun-Ichi Yamamoto's work exemplifies the intersection of biotechnology and medical research, with his patents paving the way for future advancements in drug development and cellular biology. His contributions continue to influence the scientific community and hold promise for addressing various health challenges.