Location History:
- Hirakata, JA (1976)
- Hirakata, JP (1981 - 1991)
- Osaka, JP (1984 - 1992)
Company Filing History:
Years Active: 1976-1992
Title: Jun'ichi Shoji: Innovator in Antibiotics and Enzyme Inhibition
Introduction
Jun'ichi Shoji is a prominent inventor based in Hirakata, Japan. He has made significant contributions to the field of pharmaceuticals, particularly in the development of novel compounds with therapeutic applications. With a total of eight patents to his name, Shoji's work has had a considerable impact on medical science.
Latest Patents
One of Shoji's latest inventions is an antibiotic known as plusbacin. This compound is characterized by a specific formula where X is L-HyPro or L-Pro, R is either --CH₃ or --CH(CH₃)₂, and n is an integer ranging from 9 to 12. The invention details a process for producing this compound by cultivating a microorganism from the genus Pseudomonas, which is capable of producing the compound in a medium, followed by the recovery of the compound from that medium. Additionally, he has developed a biologically pure culture of Pseudomonas sp. PB-6250 that produces this compound.
Another significant patent is for a phospholipase A2 inhibitor. This compound is defined by a specific formula where the wave line indicates either an alpha-bond or a beta-bond. This invention is particularly useful as a phospholipase A2 inhibitor, and it includes a process for producing the compound, a pharmaceutical composition containing it, and a cell culture of the microorganism Thielavia terricola RF-143 that produces the compound.
Career Highlights
Jun'ichi Shoji is currently associated with Shionogi & Company Limited, where he continues to innovate in the pharmaceutical sector. His work has been instrumental in advancing the understanding and treatment of various medical conditions through the development of new compounds.
Collaborations
Shoji has collaborated with notable colleagues, including Kouichi Matsumoto and Kentaro Tanaka. These partnerships have fostered a collaborative environment that enhances the research and development of innovative pharmaceutical solutions.
Conclusion
Jun'ichi Shoji's contributions to the field of pharmaceuticals, particularly through his patents on antibiotics and enzyme inhibitors, highlight his role as a key innovator. His work continues to influence medical science and improve therapeutic options for patients.