This inventor holds 2 USPTO granted patents. Top assignee: Genexine Co., Ltd.. Active years: 2007-2011.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Location History:
- Kyungsangbuk-do, KR (2007)
- Pohang-si, KR (2011)
Company Filing History:
Years Active: 2007-2011
Title: Innovations by Jun Chang in DNA Vaccine Adjuvants
Introduction
Jun Chang is a notable inventor based in Pohang-si, South Korea. He has made significant contributions to the field of biotechnology, particularly in the development of DNA vaccine adjuvants. With a total of 2 patents, his work focuses on enhancing immune responses to combat various diseases.
Latest Patents
One of Jun Chang's latest patents involves the genes of the IL-12P40 subunit mutated to improve the activity of IL-12. This invention relates to a mutant gene that can produce IL-12 (interleukin 12) of both human and mouse origin with high activity. The expression vector containing this mutant gene is designed for use as a DNA vaccine adjuvant. Specifically, the IL-12P40 mutant gene inhibits the secretion of IL-12P40 while allowing for the normal secretion of active IL-12P70. This is achieved by mutating the Asn-222 (human) or Asn-220 (mouse) amino acids of IL-12P40, which acts as a competitive inhibitor of the active form of IL-12, IL-12P70. The implications of this invention are significant, as it can be utilized in DNA vaccination and gene therapy against various diseases, including AIDS, hepatitis C, hepatitis B, cancer, influenza, tuberculosis, and malaria, all of which require robust cellular immune responses for effective therapy.
Career Highlights
Jun Chang is currently associated with Genexine Co., Ltd., where he continues to innovate in the field of biotechnology. His work has garnered attention for its potential applications in improving vaccine efficacy and therapeutic strategies.
Collaborations
Some of his notable coworkers include Young Chul Sung and Sung Hee Lee, who contribute to the collaborative efforts in advancing their research and innovations.
Conclusion
Jun Chang's contributions to the field of biotechnology, particularly through his patents related to DNA vaccine adjuvants, highlight his role as an influential inventor. His work not only advances scientific knowledge but also holds promise for improving public health outcomes.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile