Company Filing History:
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Years Active: 2018
Title: Julio Javier Carmelo: Innovator in Immuno-Modulating Properties
Introduction
Julio Javier Carmelo is a notable inventor based in Buenos Aires, Argentina. He has made significant contributions to the field of immunology through his innovative research and patents. His work focuses on the development of Galectin-1 polypeptide variants that have important immuno-modulating properties.
Latest Patents
Carmelo holds a patent for "GAL-1 variants having immuno-modulating properties and methods of using the same." This patent describes Galectin-1 polypeptide variants that include a mutation of the histidine residue at position 52 of the full-length amino acid sequence of native human Gal-1. The mutation involves substituting histidine with either tyrosine or asparagine, which provides resistance to acidosis that would otherwise deactivate native human Gal-1. Additionally, these variants may include further mutations of the cysteine residue at positions 2, 16, or 88, with substitutions to serine, enhancing resistance to oxidation.
Career Highlights
Throughout his career, Julio Javier Carmelo has worked with esteemed organizations such as the National Scientific and Technical Research Council (CONICET) and Fundación Sales. His research has contributed to advancements in understanding the immunological functions of Galectin-1 and its potential therapeutic applications.
Collaborations
Carmelo has collaborated with notable colleagues in his field, including Gabriel Adrián Rabinovich and Santiago Di Lella. These partnerships have fostered a collaborative environment that enhances research outcomes and innovation.
Conclusion
Julio Javier Carmelo is a distinguished inventor whose work on Galectin-1 variants has the potential to impact immunology significantly. His contributions through patents and collaborations highlight his commitment to advancing scientific knowledge and therapeutic solutions.