Company Filing History:

6 out of 174

Agouron Pharmaceuticals, Inc.

patents

Abbott Laboratories Corporation

patents

4. 1 out of 1

Agouron Phramaceuticals, Inc.

patent

5. 2 out of 832,680

Other

patents

where one patent can have more than one assignee

Years Active: 1996-2002

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11 patents (USPTO):Sort by Forward CitationsExplore Patents

1. 6472534 - Methods for the preparation of intermediates in the synthesis of HIV-protease inhibitors (2002-10-29),

2. 6465661 - Methods of making HIV-protease inhibitors and intermediates for making HIV-protease inhibitors (2002-10-15),

3. 6403799 - Methods for the preparation of intermediates in the synthesis of HIV-protease inhibitors (2002-06-11),

4. 6392067 - Methods of making HIV-protease inhibitors and intermediates for making HIV-protease inhibitors (2002-05-21),

5. 6316625 - Methods of making HIV-protease inhibitors and intermediates for making HIV-protease inhibitors (2001-11-13),

6. 6117999 - Methods of making HIV-protease inhibitors and intermediates for making (2000-09-12),

7. 6084107 - Intermediates for making HIV-protease inhibitors (2000-07-04),

8. 5925759 - Methods of making HIV-protease inhibitors and intermediates for making (1999-07-20),

9. 5922849 - Process for preparation of N-demethyl-4'-deoxy-erthromycins A and B (1999-07-13),

10. 5705647 - Intermediates for making HIV-protease inhibitors (1998-01-06),

11. 5580989 - Process for the preparation of N-4-[(substituted phenyl)alkylheterocyclic]- (1996-12-03),

Title: Juliette K Busse: Innovator in HIV-Protease Inhibitors

Introduction

Juliette K Busse is a prominent inventor based in San Diego, CA (US). She has made significant contributions to the field of medicinal chemistry, particularly in the development of HIV-protease inhibitors. With a total of 11 patents to her name, her work has had a substantial impact on the treatment of HIV.

Latest Patents

Her latest patents include innovative methods for the preparation of intermediates in the synthesis of HIV-protease inhibitors. One notable patent describes methods for converting tetrahydran derivatives into oxazolines, which serve as key reaction intermediates for the preparation of nelfinavir. Additionally, she has developed methods for creating chiral amino alcohols from epoxy-tetrahydrofuran. These advancements are crucial for the synthesis of compounds that inhibit the biological activity of the HIV protease enzyme, effectively halting the replication of the HIV virus.

Career Highlights

Throughout her career, Juliette has worked with notable companies such as Agouron Pharmaceuticals, Inc. and Japan Tobacco Inc. Her expertise in medicinal chemistry has allowed her to contribute to groundbreaking research and development in the pharmaceutical industry.

Collaborations

Juliette has collaborated with esteemed colleagues, including Bennett C Borer and Srinivasan Babu. These partnerships have further enhanced her research and innovation in the field.

Conclusion

Juliette K Busse's contributions to the development of HIV-protease inhibitors exemplify her dedication to advancing medical science. Her innovative methods and collaborative efforts continue to influence the pharmaceutical landscape.

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