Company Filing History:
Years Active: 1995-1999
Title: Innovations of Julie A Dickson
Introduction
Julie A Dickson is a prominent inventor based in Raleigh, NC (US). She has made significant contributions to the field of biotechnology, particularly in the amplification of RNA targets. With a total of 5 patents to her name, her work has had a substantial impact on molecular biology.
Latest Patents
One of her latest patents involves the Strand Displacement Amplification (SDA) of RNA targets. This innovative method, referred to as reverse transcription SDA (rtSDA), can be performed as either a two-step or a one-step process. In the one-step process, cDNA copies of an RNA target sequence are generated and amplified concurrently. The rtSDA reaction conditions allow a conventional reverse transcriptase and a DNA-dependent polymerase to function together in a single reaction, producing and amplifying cDNA. Another notable patent focuses on the DNA polymerase III .beta.-subunit from mycobacteriophage DS6A. This mycobacteriophage has been characterized to specifically infect all species of the TB complex, while not affecting other mycobacteria species. The DNA sequence analysis of DS6A revealed potential open reading frames, including one that encodes a protein analogous to gp37 of mycobacteriophage L5. This discovery allows for the identification of cloning sites for the insertion of reporter genes, making DS6A a valuable tool for the specific detection and identification of TB complex species.
Career Highlights
Julie A Dickson is currently employed at Becton Dickinson and Company Limited, where she continues to advance her research and innovations. Her work has been instrumental in developing new methodologies that enhance the understanding and treatment of various diseases.
Collaborations
Some of her notable coworkers include Robert E Pearson and Paul Theodore Hamilton. Their collaborative efforts have contributed to the success of her projects and the advancement of their shared goals in biotechnology.
Conclusion
Julie A Dickson's contributions to the field of biotechnology through her innovative patents and collaborative work highlight her as a leading figure in her area of expertise. Her ongoing research continues to pave the way for advancements in molecular biology and disease detection.