Jueren Lou

Title: Innovations of Jueren Lou in Uricase Development

Introduction

Jueren Lou is a notable inventor based in Shanghai, China. He has made significant contributions to the field of biochemistry, particularly in the development of mutant-type uricase. His work focuses on enhancing the properties of uricase through innovative modifications.

Latest Patents

Jueren Lou holds a patent for a "Mutant-type uricase, PEG modified mutant-type uricase, and application thereof." This invention involves a mutant-type uricase that has a cysteine residue introduced by recombination. The cysteine residue is strategically located in an inactive region of the uricase, and one or more polyethylene glycols (PEGs) are coupled to the mutant-type uricase. The resulting PEGylated mutant-type uricase exhibits characteristics such as a prolonged half-life, product uniformity, and stable enzyme activity. This invention has a promising range of future applications.

Career Highlights

Jueren Lou is associated with the Shanghai Institute of Biological Products Co., Ltd. His work at this institute has allowed him to focus on innovative solutions in the field of biological products. His research has the potential to impact various medical applications, particularly in treating conditions related to uric acid levels.

Collaborations

Jueren Lou has collaborated with notable colleagues, including Yun Jiang and Linqiu Huang. These collaborations have contributed to the advancement of research in the field of biochemistry and the development of innovative products.

Conclusion

Jueren Lou's contributions to the field of uricase development highlight the importance of innovation in biochemistry. His patented work on PEGylated mutant-type uricase showcases the potential for significant advancements in medical applications.