Juan Ruiz

Title: Innovations of Juan Ruiz in Ribozyme Technology

Introduction

Juan Ruiz is a notable inventor based in Pamplona, Spain. He has made significant contributions to the field of molecular biology, particularly through his innovative work on ribozymes. His research focuses on the development of self-cleaving ribozymes, which have potential applications in gene regulation and RNA manipulation.

Latest Patents

Juan Ruiz holds a patent for a multimeric self-cleaving ribozyme. This invention pertains to a multimeric self-cleaving ribozyme comprising multiple repeating units. Each unit contains a ribozyme with a catalytic domain and an antisense domain, along with a target recognition sequence recognized by the antisense domain. The ribozyme cleavage site facilitates self-cleavage, making it a valuable tool for various biotechnological applications. The patent also includes constructs comprising DNA encoding the multimeric self-cleaving ribozyme, cells stably transformed with these constructs, and methods for cleaving RNA, regulating gene expression, and generating molecular weight ladders.

Career Highlights

Juan Ruiz is affiliated with the University of Connecticut, where he continues to advance his research in ribozyme technology. His work has garnered attention for its innovative approach to molecular biology and its potential impact on genetic engineering.

Collaborations

Juan Ruiz collaborates with George Y Wu, enhancing the scope and depth of his research endeavors. Their partnership exemplifies the collaborative spirit in scientific research, leading to groundbreaking discoveries in the field.

Conclusion

Juan Ruiz's contributions to ribozyme technology highlight his innovative spirit and dedication to advancing molecular biology. His patent on the multimeric self-cleaving ribozyme represents a significant step forward in the field, with promising applications in gene regulation and RNA manipulation.