Joyce A Running

Title: **Inventor Spotlight: Joyce A Running**

Introduction

Joyce A Running is an esteemed inventor based in Concord, California, known for her significant contributions to the field of biotechnology. With a formidable portfolio that includes five patents, her work primarily focuses on the development of innovative nucleic acid probes, which are crucial for enhancing diagnostic assays.

Latest Patents

Among Joyce's latest patents, two stand out for their inventive methodologies and applications. The first patent describes **nucleic acid probes immobilized on polystyrene surfaces**. This innovative technique involves a multi-step process to cleanse the surface and attach the probes effectively. The process enhances solution phase nucleic acid sandwich hybridization assays, particularly those employing large branched DNA amplification multimers. It consists of washing the surface with a strong acid and a base, adsorbing a polypeptide with primary amino groups, covalently bonding the probes through a base-stable bifunctional crosslinking agent, and simulating hybridization conditions.

The second notable patent focuses on **HBV capture and amplifier probes for use in solution phase sandwich**. This invention features novel DNA probe sequences specific for detecting Hepatitis B Virus (HBV) in samples, showcasing how amplified nucleic acid hybridization assays can be simplified and made more efficient.

Career Highlights

Joyce A Running is currently affiliated with Chiron Corporation, where her innovative research continues to make profound impacts in the biomedical field. Her role involves the design and enhancement of protocols for nucleic acid hybridization that could significantly improve diagnostic capabilities.

Collaborations

Throughout her career, Joyce has collaborated with several esteemed professionals, including Michael S Urdea and Janice A Kolberg. These partnerships have led to advancements in her projects and contributed to the successful development of her patented technologies.

Conclusion

Joyce A Running exemplifies innovation in the biotechnology space, with her expertise and inventive spirit driving forward significant advancements. Her patents not only reflect her dedication to research and development but also showcase the potential for improving diagnostic techniques that can benefit many. As the field continues to evolve, inventors like Joyce pave the way for future technological breakthroughs.