Company Filing History:
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Years Active: 2011-2015
Title: The Innovative Contributions of Inventor Josh Grieger
Introduction
Josh Grieger is an accomplished inventor based in Chapel Hill, North Carolina, recognized for his contributions to the field of biotechnology. With a focus on engineering parvovirus capsids, he holds two patents that highlight his innovative approach to genetic engineering and virology.
Latest Patents
Grieger's latest patents revolve around the concept of chimeric vectors. The present invention is based, in part, on the discovery that parvovirus (including adeno-associated virus, or AAV) capsids can be engineered to incorporate small, selective regions from other parvoviruses that confer desirable properties. The inventors have discovered that in some cases, as little as a single amino acid insertion or substitution from a first parvovirus into the capsid structure of another parvovirus is sufficient to confer one or more of the desirable properties of the first parvovirus to the resulting chimeric parvovirus. This also allows for the conferring of properties not exhibited by the original parvovirus or that are present only to a lesser extent.
Career Highlights
Josh Grieger has had a significant impact on the research and innovation landscape through his roles at notable institutions including the University of North Carolina at Chapel Hill and the University of Florida Research Foundation. These experiences have allowed him to delve deep into the engineering of viral capsids, paving the way for advancements in gene therapy and related fields.
Collaborations
Throughout his career, Grieger has collaborated with esteemed coworkers such as Dawn E. Bowles and Chengwen Li. These collaborative efforts have enhanced his research initiatives and contributed to the successful development of his patented innovations.
Conclusion
With two patents to his name, Josh Grieger continues to contribute to the field of biotechnology through innovative research on chimeric vectors. His work exemplifies the importance of persistence and creativity in the field of invention, and he remains a notable figure in advancing genetic engineering technologies.