Company Filing History:
Years Active: 2023-2025
Title: Joseph Michael Sheridan: Innovator in Biochemical Synthesis
Introduction
Joseph Michael Sheridan is a notable inventor based in Reinach, Switzerland. He has made significant contributions to the field of biochemical synthesis, particularly in the development of norcoclaurine synthases and cytochrome P450 enzymes. With a total of 2 patents, Sheridan's work is paving the way for advancements in the production of important biochemical compounds.
Latest Patents
Sheridan's latest patents include innovations in norcoclaurine synthases with increased activity. This invention focuses on specific mutations that enhance the condensation of 4-HPAA and dopamine to produce (S)-norcoclaurine, as well as 3,4-DhPAA and dopamine to yield (S)-norlaudanosoline. The identified mutations correspond to specific positions in the synthase, which are crucial for increasing activity compared to the wild type.
Another significant patent involves the demethylation of reticuline and its derivatives using fungal cytochrome P450. This invention describes recombinant host cells that express genes encoding a cytochrome P450 enzyme capable of N-demethylating and/or O-demethylating reticuline. The methods developed provide access to naturally unavailable and chemically challenging starting materials for opioids.
Career Highlights
Joseph Michael Sheridan is currently associated with River Stone Biotech LLC, where he continues to innovate in the field of biochemical research. His work has garnered attention for its potential applications in pharmaceuticals and natural product synthesis.
Collaborations
Sheridan collaborates with esteemed colleagues, including Markus Schwab and Philipp Friedrich Berninger. Their combined expertise enhances the research and development efforts at River Stone Biotech LLC.
Conclusion
Joseph Michael Sheridan is a prominent figure in the field of biochemical synthesis, with a focus on enhancing enzyme activity and developing innovative methods for producing valuable compounds. His contributions are significant in advancing the understanding and application of biochemical processes.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.