This inventor holds 4 USPTO granted patents. Top assignees: Smithkline Instruments, Inc., Leland Stanford Junior University, Sri International. Active years: 1976-1982.
Company Filing History:
2 out of 16 
1 out of 5,509 
1 out of 1,358 
Years Active: 1976-1982
Title: Joseph I De Graw: Innovator in Pharmaceutical Chemistry
Introduction
Joseph I De Graw is a notable inventor based in Sunnyvale, CA (US). He has made significant contributions to the field of pharmaceutical chemistry, holding a total of 4 patents. His work primarily focuses on developing novel compounds that serve as potential therapeutic agents.
Latest Patents
One of his latest patents involves oxoalkanoic acid derivatives as inhibitors of angiotensin converting enzyme. This invention relates to novel analogs of proline terminal tripeptides and related compounds. The compounds are potent inhibitors of angiotensin converting enzyme and are useful as antihypertensive agents. Another significant patent includes N-sec-alkyl analogs of norcodeine and normorphine, which are novel derivatives wherein the sec-alkyl group contains either four or five carbon atoms. These derivatives exhibit strong agonist potency combined with strong antagonist qualities, indicating low addiction potential. The norcodeine analogs are particularly useful as intermediates in preparing the corresponding normorphine compounds.
Career Highlights
Throughout his career, Joseph has worked with various companies, including Smithkline Instruments, Inc. His innovative work has led to advancements in the pharmaceutical industry, particularly in the development of analgesics and antihypertensive agents.
Collaborations
Joseph has collaborated with notable individuals in his field, including M James Barrett and Ronald G Almquist. These collaborations have contributed to the success of his inventions and patents.
Conclusion
Joseph I De Graw is a distinguished inventor whose work in pharmaceutical chemistry has led to the development of important therapeutic agents. His contributions continue to impact the field positively, showcasing the importance of innovation in healthcare.