This inventor holds 6 USPTO granted patents and 2 published patent applications, plus 1 CIPO patent and 2 EPO patents. Top assignees: The University of North Carolina at Chapel Hill, University of Florida Research Foundation Inc.. Active years: 2002-2015.
Location History:
- Carrboro, NC (US) (2002 - 2011)
- Secane, PA (US) (2011 - 2015)
Company Filing History:
6 out of 1,325 
2 out of 3,046 
Years Active: 2002-2015
Title: Joseph E Rabinowitz: Innovator in Gene Therapy
Introduction
Joseph E Rabinowitz is a prominent inventor based in Carrboro, NC (US). He has made significant contributions to the field of gene therapy, holding a total of 6 patents. His work focuses on the engineering of parvovirus vectors for therapeutic applications.
Latest Patents
One of his latest patents is related to chimeric vectors. This invention is based on the discovery that parvovirus capsids can be engineered to incorporate selective regions from other parvoviruses, which confer desirable properties. The inventors found that even a single amino acid insertion or substitution from one parvovirus into another can create a chimeric parvovirus that exhibits enhanced properties. Another notable patent involves methods and compounds for the controlled release of recombinant parvovirus vectors. This invention utilizes recombinant adeno-associated viruses (rAAV) to deliver genes for gene therapy, affixed to support matrixes such as sutures and grafts.
Career Highlights
Joseph has worked with esteemed institutions, including the University of North Carolina at Chapel Hill and the University of Florida Research Foundation Inc. His research has significantly advanced the understanding and application of viral vectors in gene therapy.
Collaborations
Throughout his career, Joseph has collaborated with notable colleagues, including Richard Jude Samulski and Chengwen Li. Their combined expertise has contributed to the success of various projects in the field.
Conclusion
Joseph E Rabinowitz is a key figure in the innovation of gene therapy, with a focus on parvovirus vectors. His patents and collaborations have paved the way for advancements in therapeutic applications, showcasing his impact on the field.