Joseph Desimone

Chapel Hill, NC, United States of America

Joseph Desimone

This inventor holds 72 USPTO granted patents and 37 published patent applications, plus 4 CIPO patents and 5 EPO patents, primarily in Nanoparticle Fabrication (CPC class A61K). Top assignees: The University of North Carolina at Chapel Hill, Synecor LLC, University of Illinois. Active years: 2000-2023. Education: Ursinus College (USA); Virginia Tech (USA).

Graduated from:
  • Ursinus College (USA)
  • Virginia Tech (USA)
USPTO Granted Patents = 72 

% Patents Active = 66.7


 

Average Co-Inventor Count = 3.0

ph-index = 20

Forward Citations = 1,802(Granted Patents)

Forward Citations (Not Self Cited) = 1,731(Dec 10, 2025)


Location History:

  • Chapel Hill, NC (US) (2000 - 2023)
  • Glen Ellyn, IL (US) (2016 - 2023)

Company Filing History:


Years Active: 2000-2023

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Areas of Expertise:
Nanoparticle Fabrication
Drug Delivery Systems
Microfluidic Devices
Decitabine Compositions
Soft Lithography
Endoprostheses
Orthodontic Appliances
Photocurable Materials
3D Fabrication
Therapeutic Agents
Micro-Nano Structures
Degradable Compounds
72 patents (USPTO):Explore Patents

Title: Joseph Desimone: Pioneering Innovations in Local Drug Delivery Systems

Introduction

Joseph Desimone, based in Chapel Hill, North Carolina, is a prolific inventor with a remarkable portfolio of six patents. His work primarily focuses on innovative methods and systems for local drug delivery, greatly impacting therapeutic approaches in medicine.

Latest Patents

Among Desimone's notable contributions are two recent patents aimed at enhancing combination therapy involving localized drug delivery and radiation. The first patent outlines a method and system for the combined local delivery of therapeutic agents using interventional devices and radiation. This inventive system utilizes a source electrode positioned near the target site, creating a localized electric field that facilitates the delivery of cargo—therapeutic agents—when exposed to this field. In conjunction, radiotherapy is applied, promoting a synergistic effect at the targeted body tissue.

The second patent introduces an interventional drug delivery system alongside associated methods. Similar to the first, this system comprises a source electrode and a counter electrode that work together to form an electric field. A reservoir containing the cargo is strategically positioned to interact with this localized field, ensuring effective delivery to the internal body tissue.

Career Highlights

Throughout his career, Joseph Desimone has made significant strides in the field of drug delivery systems. He has been associated with prestigious institutions, including the University of North Carolina at Chapel Hill, where he has contributed his knowledge and expertise to advance research in therapeutic innovations.

Collaborations

Desimone's journey has been shaped by collaborative efforts with notable colleagues such as James Byrne and Joel Tepper. Their collective endeavors have fostered a rich environment for innovation, driving forward the development of groundbreaking therapeutic methods.

Conclusion

In summary, Joseph Desimone stands out as a leader in medical innovation, particularly in local drug delivery systems. His recent patents reflect his commitment to enhancing treatment efficacy through creative technological solutions. With each invention, he continues to push the boundaries of what's possible in the realm of healthcare.

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