The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 06, 2026

Filed:

Sep. 22, 2022
Applicants:

The Board of Trustees of the Leland Stanford Junior University, Stanford, CA (US);

The University of North Carolina AT Chapel Hill, Chapel Hill, NC (US);

Inventors:

Joseph M. Desimone, Stanford, CA (US);

Gunilla B. Jacobson, Stanford, CA (US);

Maria T. Dulay, Stanford, CA (US);

Brian J. Lee, Stanford, CA (US);

Kai-Wen Hsiao, Stanford, CA (US);

Netra Rajesh, Stanford, CA (US);

Madison M. Driskill, Stanford, CA (US);

Audrey Shih, Stanford, CA (US);

Jillian Perry, Durham, NC (US);

Shaomin Tian, Chapel Hill, NC (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/00 (2006.01); B29C 64/135 (2017.01); B29C 64/232 (2017.01); B29C 64/255 (2017.01); B29C 64/268 (2017.01); B29K 23/00 (2006.01); B29L 31/00 (2006.01); B33Y 10/00 (2015.01); B33Y 30/00 (2015.01); B33Y 70/00 (2020.01); B33Y 80/00 (2015.01); C08F 122/10 (2006.01);
U.S. Cl.
CPC ...
A61K 9/0021 (2013.01); B29C 64/135 (2017.08); B29C 64/232 (2017.08); B29C 64/268 (2017.08); B33Y 10/00 (2014.12); B33Y 30/00 (2014.12); B33Y 70/00 (2014.12); B33Y 80/00 (2014.12); C08F 122/1006 (2020.02); B29C 64/255 (2017.08); B29K 2023/08 (2013.01); B29L 2031/7544 (2013.01);
Abstract

Aspects of the present disclosure include polymeric structures (e.g., microneedles) having a lattice microstructure composed of one or more lattice cell units. Polymeric structures according to certain embodiments have repeating lattice cell units that are formed by high resolution continuous liquid interface production. Aspects also include systems for making polymeric structures having a lattice microstructure. Systems according to certain embodiments include a micro-digital light projection system having a light beam generator component and a light projection monitoring component and a liquid interface polymerization module having a build elevator and a build surface configured for generating the polymeric lattice microstructure from a polymerizable composition positioned therebetween. Methods for making polymeric structures having a lattice microstructure with the subject systems are also provided. Patches having an array of polymeric microneedles for applying to a skin surface of a subject are also described. In some embodiments, patches include microneedles that contain an active agent compound (e.g., an immunogenic active agent). Methods for applying the patches to the skin surface of a subject are also described.


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