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Years Active: 2014-2015
Title: Joseph Cortese: Innovator in Malaria Treatment
Introduction
Joseph Cortese is a notable inventor based in Quincy, MA (US), recognized for his contributions to the field of medicinal chemistry. He holds 2 patents that focus on innovative methods for treating malaria, showcasing his commitment to addressing significant health challenges.
Latest Patents
Cortese's latest patents include the development of 2-aminoindole compounds and methods for the treatment of malaria. The present invention relates to methods of treating a subject with malaria by administering a 2-aminoindole compound represented by a specific formula. The values and preferred values of the variables in this structural formula are defined within the patent documentation. Additionally, he has identified and characterized inhibitors of dihydroorotate dehydrogenase (DHODH) that exhibit high specificity and submicromolar efficacy against cultured parasite strains. These inhibitors demonstrate drug-like properties and are not overtly cytotoxic, making them promising candidates for further development.
Career Highlights
Throughout his career, Joseph Cortese has worked with prominent organizations such as Genzyme Corporation and Harvard College. His work in these institutions has allowed him to collaborate with leading experts in the field and contribute to groundbreaking research.
Collaborations
Cortese has had the opportunity to work alongside esteemed colleagues, including Jon Clardy and Dyann F Wirth. Their collaborative efforts have further advanced the research and development of effective treatments for malaria.
Conclusion
Joseph Cortese's innovative work in the field of malaria treatment highlights his dedication to improving global health through scientific advancements. His patents and collaborations reflect a significant contribution to the fight against infectious diseases.