Josef Mayrhofer

Title: Innovations by Josef Mayrhofer

Introduction

Josef Mayrhofer is a notable inventor based in Vienna, Austria. He has made significant contributions to the field of virology, particularly in the development of modified poxviruses. His work has implications for vaccine development and virus replication inhibition.

Latest Patents

Josef Mayrhofer holds 2 patents. His latest patents include innovations related to modified poxviruses, specifically a modified smallpox virus vaccine based on a recombinant drug-sensitive vaccinia virus. This invention provides recombinant poxviruses that contain an integrated exogenous sequence, such as a foreign gene, encoding a prodrug converting polypeptide. This polypeptide can convert a prodrug to a drug that prevents virus replication or is otherwise toxic to the virus. The recombinant poxviruses can be suitable for use as vaccines. The invention also outlines methods of inhibiting virus replication, methods of vaccination, and methods of treating vaccinated subjects showing signs or at risk for vaccination-induced disease.

Career Highlights

Throughout his career, Josef Mayrhofer has worked with prominent companies such as Baxter International Inc. and Baxter Healthcare SA. His experience in these organizations has contributed to his expertise in the field of virology and vaccine development.

Collaborations

Josef has collaborated with notable individuals in his field, including Falko-Guenter Falkner and Georg Holzer. These collaborations have likely enhanced his research and development efforts.

Conclusion

Josef Mayrhofer's innovative work in the field of modified poxviruses and vaccine development showcases his significant contributions to science and medicine. His patents and collaborations reflect a commitment to advancing virology and public health.