The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 11, 2006
Filed:
Mar. 14, 2003
Falko-guenter Falkner, Orth/Donau, AT;
Georg Holzer, Vienna, AT;
Sogue Coulibaly, Vienna, AT;
Josef Mayrhofer, Vienna, AT;
Falko-Guenter Falkner, Orth/Donau, AT;
Georg Holzer, Vienna, AT;
Sogue Coulibaly, Vienna, AT;
Josef Mayrhofer, Vienna, AT;
Baxter International Inc., Deerfield, IL (US);
Baxter Heathcare S.A., Zurich, CH;
Abstract
The present invention provides recombinant poxviruses, such as vaccinia virus, that contain an integrated exogenous sequence, such as a foreign gene, encoding a prodrug converting polypeptide that can convert a prodrug to a drug that prevents virus replication or is otherwise toxic to the virus. The recombinant poxviruses can be suitable for use as vaccines. The invention also provides, among other things, methods of inhibiting virus replication, methods of vaccination and methods of treating vaccinated subjects showing signs or otherwise at risk for of vaccination-induced disease.