Georg Holzer

Title: Georg Holzer: Innovator in Modified Poxviruses

Introduction

Georg Holzer is a notable inventor based in Vienna, Austria. He has made significant contributions to the field of virology, particularly in the development of modified poxviruses. With a total of five patents to his name, Holzer's work focuses on innovative vaccine technologies.

Latest Patents

Holzer's latest patents include groundbreaking research on modified poxviruses, specifically a modified smallpox virus vaccine based on a recombinant drug-sensitive vaccinia virus. This invention provides recombinant poxviruses that contain an integrated exogenous sequence, such as a foreign gene, encoding a prodrug converting polypeptide. This polypeptide can convert a prodrug to a drug that prevents virus replication or is otherwise toxic to the virus. The recombinant poxviruses are suitable for use as vaccines. Additionally, the invention outlines methods for inhibiting virus replication, methods of vaccination, and methods for treating vaccinated subjects who show signs or are at risk of vaccination-induced disease.

Career Highlights

Throughout his career, Georg Holzer has worked with prominent companies in the biotechnology sector. Notable among these are Immuno Aktiengesellschaft and Baxter International Inc. His work in these organizations has contributed to advancements in vaccine development and virology.

Collaborations

Holzer has collaborated with esteemed colleagues in his field, including Friedrich Dorner and Falko-Guenter Falkner. These collaborations have furthered his research and innovation in the area of modified poxviruses.

Conclusion

Georg Holzer's contributions to the field of virology, particularly through his innovative patents on modified poxviruses, highlight his role as a significant inventor. His work continues to influence vaccine development and offers promising solutions for viral diseases.