Company Filing History:
5 out of 414 
2 out of 532 
Years Active: 2018-2025
Title: Innovations by Inventor Jose Cancelas
Introduction
Jose Cancelas is a notable inventor based in Cincinnati, OH, known for his groundbreaking contributions to the field of medical science. With a total of four patents to his name, he has been instrumental in developing innovative solutions, particularly in cancer treatment and blood storage.
Latest Patents
Among his latest patents, Jose has focused on two significant areas:
1. **Compositions and methods for treating cancer** - His research on a small molecule compound, IODVA1, has demonstrated cellular inhibitory activity against various transformed cell lines, including Ras-driven cells. IODVA1 not only decreases cell-cell and cell-extracellular matrix interactions but also effectively reduces the growth of Ras-driven tumors. Additionally, he has synthesized a compound named NIRA2, showcasing promising in vitro and in vivo efficacy against models of Philadelphia chromosome-positive (Ph+) B-cell acute lymphoblastic leukemia (B-ALL) and colon adenocarcinoma xenografts.
2. **Platelet storage methods and compositions for the same** - This patent involves compositions and methods designed to slow, prevent, or reverse platelet damage, particularly during blood banking or refrigeration. The composition may include a combination of inhibitors such as a RAC inhibitor, a CDC42 inhibitor, and a RHOA inhibitor, alongside a pharmaceutically acceptable carrier.
Career Highlights
Jose Cancelas has made substantial contributions while working at esteemed institutions such as the Children’s Hospital Medical Center and the University of Cincinnati. His work in these organizations has allowed him to focus on critical medical research and push the boundaries of innovation.
Collaborations
Throughout his career, Jose has collaborated with notable colleagues, including Yi Zheng and Nicolas Nassar. These partnerships have further enriched his research and innovation trajectory, enabling him to tackle complex medical challenges.
Conclusion
In conclusion, Jose Cancelas stands out as a dedicated inventor whose work substantially impacts the fields of oncology and transfusion medicine. His patents reflect a commitment to advancing medical solutions that can potentially save lives and improve patient outcomes. Through his innovative research and collaborations, he continues to contribute to the scientific community and inspire future advancements.