Company Filing History:
Years Active: 2005-2010
Title: Innovations of Jörg Windisch in Recombinant Protein Production
Introduction
Jörg Windisch is a notable inventor based in Kramsach, Austria. He has made significant contributions to the field of biotechnology, particularly in the area of recombinant protein production. With a total of 3 patents, Windisch's work has advanced the methods used in the production of heterologous proteins.
Latest Patents
Windisch's latest patents include innovative processes that enhance the efficiency of protein production. One of his patents focuses on expression vectors, transformed host cells, and fermentation processes for the production of recombinant polypeptides. This invention relates to an expression vector that comprises a polynucleotide encoding a fusion protein, which includes the signal sequence of the gac gene and a polypeptide of interest. The invention also describes a prokaryotic host cell transformed with such an expression vector and a process for producing a polypeptide of interest using the host cell and expression vector.
Another significant patent by Windisch involves the production of heterologous proteins using an Npro autoprotease of a pestivirus. This invention outlines a process for the recombinant production of a desired heterologous polypeptide with a clearly defined homogenous N-terminus in a bacterial host cell. The process includes expressing a fusion comprising a peptide with the autoproteolytic activity of an autoprotease N of a pestivirus and the heterologous polypeptide in the form of cytoplasmic inclusion bodies. The inclusion bodies are then isolated and treated to cleave the desired heterologous polypeptide autoproteolytically by the N activity of the fusion protein.
Career Highlights
Jörg Windisch is currently associated with Sandoz AG, a global leader in generic pharmaceuticals and biosimilars. His work at Sandoz has allowed him to apply his innovative ideas in a practical setting, contributing to advancements in the pharmaceutical industry.
Collaborations
Windisch has collaborated with notable colleagues such as Franz Knauseder and Günter Stempfer. These collaborations have fostered a productive environment for innovation and research in biotechnology.
Conclusion
Jörg Windisch's contributions to the field of recombinant protein production through his patents and work at Sandoz AG highlight his role as a significant inventor in biotechnology. His innovative approaches continue to influence the methods used in the production