Jordan S Fridman

Title: Innovations and Contributions of Jordan S. Fridman

Introduction

Jordan S. Fridman is a notable inventor based in Newark, DE (US). He has made significant contributions to the field of biomedical research, particularly in cancer treatment. With a total of seven patents to his name, Fridman has developed innovative solutions that address critical health challenges.

Latest Patents

Fridman's latest patents include compositions, methods, and kits relating to HER-2 cleavage. This invention focuses on the ADAM-mediated cleavage of Her-2, which is crucial for developing treatments for cancer, especially breast cancer. The invention highlights the synergistic effect between the inhibition of Her-2 cleavage by an ADAM and certain cytostatic and cytotoxic compounds, which can inhibit tumor cell proliferation and induce cell death. Another significant patent involves heteroaryl substituted pyrrolo[2,3-B] pyridines and pyrrolo[2,3-B] pyrimidines that modulate the activity of Janus kinases. These compounds are useful in treating various diseases related to Janus kinase activity, including immune-related diseases and cancer.

Career Highlights

Throughout his career, Fridman has worked with prominent companies such as Incyte Corporation and Incyte Holdings Corporation. His work in these organizations has allowed him to advance his research and contribute to the development of innovative therapies.

Collaborations

Fridman has collaborated with notable colleagues, including Krishna Vaddi and James David Rodgers. These partnerships have facilitated the exchange of ideas and expertise, further enhancing his contributions to the field.

Conclusion

Jordan S. Fridman is a distinguished inventor whose work has significantly impacted cancer treatment and biomedical research. His innovative patents and collaborations reflect his commitment to advancing healthcare solutions.