Company Filing History:
8 out of 5,445 
2 out of 35 
1 out of 11 Years Active: 1987-2014
Title: The Innovative Contributions of Jonathan W Uhr
Introduction
Jonathan W Uhr is a prominent inventor based in Dallas, TX, known for his significant contributions to the field of cancer research. With a total of 12 patents to his name, Uhr has developed groundbreaking technologies that enhance the understanding and treatment of tumors. His work focuses on innovative methods and compositions that have the potential to revolutionize cancer therapies.
Latest Patents
Uhr's latest patents include "Compositions and methods for homoconjugates of antibodies which induce growth arrest or apoptosis of tumor cells." This invention reveals that monoclonal antibodies (MAbs) with minimal signaling activity as monomers can become powerful anti-tumor agents when converted into homoconjugates. These homoconjugates exhibit anti-growth activity by signaling G/G arrest or apoptosis, depending on the specific cell surface molecule they bind to. Notably, this activity does not require an Fc portion, making these conjugates potent anti-tumor agents.
Another significant patent is "Methods and reagents for the rapid and efficient isolation of circulating cancer cells." This highly sensitive assay combines immunomagnetic enrichment with multiparameter flow cytometric and immunocytochemical analysis to detect, enumerate, and characterize carcinoma cells in the blood. The assay can identify one epithelial cell or less in 1 ml of blood, demonstrating greater sensitivity than conventional PCR or immunohistochemistry by 1-2 orders of magnitude. Additionally, this assay facilitates the biological characterization and staging of carcinoma cells.
Career Highlights
Throughout his career, Jonathan W Uhr has worked with esteemed organizations, including the University of Texas System and Immunivest Corporation. His innovative research and dedication to advancing cancer treatment have made him a respected figure in the scientific community.
Collaborations
Uhr has collaborated with notable colleagues, including Ellen S Vitetta and Leon W M M Terstappen, further enhancing the impact of his research through shared expertise and knowledge.
Conclusion
Jonathan W Uhr's contributions to cancer research through his innovative patents and collaborations highlight his commitment to improving treatment options for patients. His work continues to inspire advancements in the field of oncology.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.