Company Filing History:
Years Active: 2000
Title: Innovations in Lyme Disease Diagnostics: The Contributions of Jonathan T. Skare
Introduction
Jonathan T. Skare, based in College Station, Texas, is a noteworthy inventor recognized for his contributions to medical biotechnology, particularly in the field of Lyme disease diagnostics. With a singular patent to his name, Skare has made significant strides in understanding and combating this debilitating disease through innovative research and development.
Latest Patents
Skare's patent focuses on the outer membrane proteins of Borrelia burgdorferi, the bacterium responsible for Lyme disease. His invention presents three critical membrane proteins: Oms28, Oms45, and Oms66, each identified by their respective molecular weights of approximately 28 kDa, 45 kDa, and 66 kDa. The patent outlines the average single-channel conductances of these proteins as 0.6, 0.22, and 9.7 nS. Furthermore, Skare's work details methods for purifying these proteins from Borrelia burgdorferi, producing antibodies specific to them, and utilizing these antibodies to induce immune responses against the pathogen. This innovative approach not only aids in diagnostics but also plays a crucial role in advancing our understanding of Lyme disease.
Career Highlights
Jonathan T. Skare is associated with the University of California, where his research focuses on the intersection of microbiology and immunology. His career is marked by a commitment to understanding the complexities of infectious diseases and developing innovative solutions to tackle them. The impact of his work is expected to enhance the detection and treatment of Lyme disease significantly.
Collaborations
Skare's research has been propelled through collaborations with esteemed colleagues, including Ellen S. Shang and Cheryl I. Champion. These partnerships have fostered an environment of innovation and knowledge-sharing, leading to advancements in the methods for isolating and purifying Borrelia burgdorferi outer membrane spanning proteins, thereby enriching the biomedical field.
Conclusion
In summary, Jonathan T. Skare's contributions to the development of diagnostic tools for Lyme disease exemplify the vital role of innovative research in combating infectious diseases. His pioneering work on Borrelia burgdorferi membrane proteins not only enhances our understanding of the bacterium but also holds promise for improved diagnostic methods, demonstrating the importance of continued innovation in medical science.