Zionsville, IN, United States of America

Jonathan H Lebowitz


Average Co-Inventor Count = 13.0

ph-index = 3

Forward Citations = 148(Granted Patents)


Company Filing History:


Years Active: 1998-2002

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3 patents (USPTO):Explore Patents

Title: The Innovative Mind of Jonathan H. Lebowitz: A Pioneer in Transcriptional Regulation

Introduction

Jonathan H. Lebowitz, an accomplished inventor based in Zionsville, Indiana, has made significant contributions to the field of transcriptional regulation. With three patents to his name, Lebowitz's research focuses on understanding the protein factors that influence gene transcription, particularly in immunoglobulin genes. His work has implications for enhancing gene expression, which can be pivotal for various applications in biotechnology and medicine.

Latest Patents

Among his latest patents, Jonathan H. Lebowitz has developed insights into nuclear factors associated with transcriptional regulation. His patented work describes constitutive and tissue-specific protein factors that bind to transcriptional regulatory elements of immunoglobulin (Ig) genes, including both promoters and enhancers. These factors were identified and isolated through an advanced assay for protein-DNA binding. Notably, the research highlights the genes encoding factors that positively regulate transcription, such as NF-kB, which can be utilized to enhance the transcription of Ig genes. The significance of this work lies in its potential applications in genetic regulation and therapeutic strategies.

Career Highlights

Lebowitz's professional journey includes notable affiliations with prestigious institutions like the Massachusetts Institute of Technology (MIT) and the President and Fellows of Harvard College. His time at these esteemed organizations has been instrumental in shaping his innovative approach to scientific challenges in molecular biology and gene expression.

Collaborations

Throughout his career, Jonathan H. Lebowitz has collaborated with prominent scientists such as David Baltimore and Ranjan Sen. These partnerships have not only enriched his research but have also contributed to broader advancements in the understanding of the molecular mechanisms underlying transcriptional regulation.

Conclusion

In summary, Jonathan H. Lebowitz stands as a significant figure in the realm of transcriptional regulation. With his innovative patents and collaborations with esteemed colleagues, he continues to pave the way for future research and applications in genetic regulation. His work remains crucial in deciphering the complexities of gene expression, ultimately contributing to the fields of biotechnology and medicine.

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