Company Filing History:
Years Active: 2002
Title: The Innovative Contributions of Jonathan D Wren
Introduction
Jonathan D Wren is a notable inventor based in Irving, TX (US). He has made significant contributions to the field of genetics through his innovative research and patents. His work focuses on computational methods for identifying polymorphic repeats in human genes, which has implications for understanding genetic variations.
Latest Patents
Jonathan D Wren holds a patent for "Polymorphic repeats in human genes." This invention provides computational methods and compositions for identifying polymorphic repeats in genes. Candidate polymorphic repeats are identified by detecting tandem repeats in a target coding sequence, scoring the repeats for polymorphic probability, and generating a dataset correlating the repeats with polymorphic probability. Actual polymorphic repeats are identified by further detecting the candidate polymorphic repeat in each of a population of different coding sequences, and determining whether the candidate polymorphic repeat is polymorphic in the population. Computationally derived polymorphic repeats are validated with phenotypic variations, and these correlates are used to detect the presence or absence of such phenotypic variation in test genes. Variances at polymorphic repeats are identified by detecting in a test gene or coding region the presence or absence of variance at a disclosed unconventional polymorphic repeat.
Career Highlights
Jonathan D Wren is affiliated with the University of Texas System, where he continues to advance his research in genetics and computational biology. His work has garnered attention for its potential applications in medical research and genetic testing.
Collaborations
Some of his notable coworkers include Harold R Garner and John Dorrance Minna, who have collaborated with him on various research projects.
Conclusion
Jonathan D Wren's innovative work in identifying polymorphic repeats in human genes showcases his significant contributions to the field of genetics. His research not only enhances our understanding of genetic variations but also paves the way for future advancements in genetic testing and medical research.
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