Jonathan C Moore

Title: Innovations of Jonathan C Moore

Introduction

Jonathan C Moore is a notable inventor based in Gainesville, FL (US). He has made significant contributions to the field of biocatalysis, particularly in the production of succinic acid and other valuable products from renewable biological feedstocks. With a total of 5 patents to his name, Moore's work exemplifies the intersection of engineering and biotechnology.

Latest Patents

One of his latest patents focuses on "Engineering the pathway for succinate production." This invention relates to biocatalysts that enable the efficient production of succinic acid from carbohydrate feedstocks. The biocatalysts developed by Moore exhibit high efficiency for growth-coupled production, achieved through genetic manipulation and metabolic evolution. Specifically, these biocatalysts can produce succinic acid at high titers and yields in mineral salts media during pH-controlled batch fermentation without the need for exogenous genetic material. The genetic modifications aim to conserve energy while eliminating alternative NADH oxidation routes, thereby enhancing succinic acid production.

Another significant patent involves "Materials and methods for efficient succinate and malate production." This invention describes genetically engineered microorganisms capable of producing succinate and malate in mineral salt media through pH-controlled batch fermentations, without the addition of plasmids or foreign genes. The methods outlined in this patent provide a streamlined approach to cultivating these genetically modified microorganisms.

Career Highlights

Jonathan C Moore is affiliated with the University of Florida Research Foundation, Incorporated. His work has been instrumental in advancing biotechnological applications that leverage renewable resources for sustainable production processes.

Collaborations

Moore has collaborated with notable colleagues such as Lonnie O'Neal Ingram and Keelnatham T Shanmugam, contributing to the collective expertise in the field of biocatalysis and genetic engineering.

Conclusion

Jonathan C Moore's innovative work in biocatalysis and genetic engineering has paved the way for more efficient production methods of succinic acid and malate. His contributions are vital for advancing sustainable practices in biotechnology.