John W Tessman

Title: The Innovations of John W Tessman

Introduction

John W Tessman is a notable inventor based in Berkeley, CA (US). He has made significant contributions to the field of enzyme preparations and nucleic acid amplification. With a total of 4 patents, Tessman has developed methods that address critical issues in biotechnology.

Latest Patents

Tessman's latest patents include innovative methods for the treatment of enzyme preparations. One of his key inventions focuses on solving the problem of contamination of protein with nucleic acid. This method renders amplifiable contaminating nucleic acid in enzyme preparations substantially unamplifiable prior to the use of the enzyme. Another significant patent involves a method for rendering ligase-based amplification products unamplifiable. This method includes sterilization techniques for ligase-based amplification products, particularly those resulting from the Ligation Amplification Reaction (LAR). The process involves treating nucleic acid after amplification to ensure it cannot serve as a template for further amplification. Tessman’s methods utilize both random and site-specific addition of sterilizing compounds, including photoactivation compounds, to achieve this goal. Additionally, self-sterilizing primers are employed, allowing for homogeneous detection of ligase-based amplification products.

Career Highlights

Throughout his career, John W Tessman has worked with various companies, including Steritech, Inc. His work has significantly impacted the field of biotechnology, particularly in the development of methods that enhance the reliability and safety of enzyme preparations.

Collaborations

Tessman has collaborated with notable individuals in his field, including Stephen T Isaacs and George D Cimino. These collaborations have contributed to the advancement of his innovative methods and patents.

Conclusion

John W Tessman is a distinguished inventor whose work in enzyme preparations and nucleic acid amplification has led to valuable patents. His innovative methods continue to influence the biotechnology industry and enhance the safety and efficacy of various applications.