John W Christman

Title: John W Christman: Innovator in Peptide Inhibitors

Introduction

John W Christman is a notable inventor based in Columbus, OH (US). He has made significant contributions to the field of peptide inhibitors, particularly in the context of calcineurin-NFAT interactions. With a total of 4 patents to his name, Christman's work has implications for various therapeutic applications.

Latest Patents

One of Christman's latest patents focuses on peptidyl inhibitors of calcineurin-NFAT interaction. This patent describes peptides and peptide conjugates that comprise calcineurin binding motifs (CNBM) which inhibit the CN-NFAT interaction. The peptides may include a hydrophobic, non-peptidic moiety (RH) that interacts with the hydrophobic pocket on a calcineurin protein. The sequences involved can vary, allowing for flexibility in design and application.

Career Highlights

Throughout his career, John W Christman has worked with the Ohio State Innovation Foundation, where he has contributed to advancing research and innovation. His expertise in peptide chemistry and molecular interactions has positioned him as a key figure in his field.

Collaborations

Christman has collaborated with notable colleagues such as Dehua Pei and Manjula Karpurapu. These partnerships have fostered a collaborative environment that enhances research outcomes and innovation.

Conclusion

John W Christman's contributions to the field of peptide inhibitors demonstrate his commitment to advancing scientific knowledge and therapeutic solutions. His innovative work continues to impact the landscape of biochemistry and pharmacology.