Company Filing History:
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Years Active: 2013-2019
Title: The Innovative Contributions of John Thomas Norton
Introduction
John Thomas Norton is a notable inventor based in San Diego, California, known for his significant contributions to the field of biomedicine. With a total of seven patents to his name, he is particularly recognized for his work on humanized antibodies and compounds aimed at treating cancer.
Latest Patents
One of Norton's most recent patents focuses on "Humanized antibodies that bind LGR5." This innovative development provides humanized anti-LGR5 antibodies that are designed for cancer treatment. These antibodies can bind to LGR5 without disrupting the LGR5-RSPO1 binding or signaling, while also having the potential to disrupt LGR5 signaling through Wnt, independent of RSPO1. Additionally, he has disclosed heavy and light chain polypeptide sequences that facilitate the binding of LGR5.
Another significant patent addresses "Compounds and methods for the prevention and treatment of tumor metastasis and tumorigenesis." This patent introduces compounds that help reduce the prevalence of the perinucleolar compartment in cells, a condition associated with various cancers. The composition includes a pharmaceutically acceptable carrier and at least one compound embodying the principles of the invention, along with methods for treating or preventing cancer in mammals.
Career Highlights
Throughout his career, John Thomas Norton has collaborated with prestigious institutions and companies, enhancing his impact on medical research and innovation. He has worked at Northwestern University and Bionomics Inc., where he honed his skills and contributed to groundbreaking advancements in biomedical research.
Collaborations
In addition to his work at established companies, Norton has collaborated with notable professionals in his field. Among his coworkers are Sui Huang and Daniel H. Appella, both of whom have played essential roles in the development of his pioneering projects. These collaborations highlight the importance of teamwork in advancing scientific research and innovation.
Conclusion
John Thomas Norton stands as a leading figure in the realm of cancer research, equipped with a wealth of knowledge and a strong patent portfolio. His innovative work on humanized antibodies and anti-cancer compounds demonstrates his commitment to improving medical treatments and patient outcomes. As he continues to innovate, Norton inspires future generations of inventors in the fight against cancer.