The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 30, 2017
Filed:
Dec. 17, 2012
The United States of America, As Represented BY the Secretary, Department of Health and Human Services, Washington, DC (US);
University of Kansas, Lawrence, KS (US);
North-western University, Evanston, IL (US);
Kevin Frankowski, Lawrence, KS (US);
Samarjit Patnaik, Gaithersburg, MD (US);
Sui Huang, Chicago, IL (US);
Juan Jose Marugan, Gaithersburg, MD (US);
John Norton, San Diego, CA (US);
Frank J. Schoenen, Lawrence, KS (US);
Noel Terrence Southall, Potomac, MD (US);
Steven Titus, Elkridge, MD (US);
Wei Zheng, Potomac, MD (US);
The United States of America, as represented by the Secretary, Department of Health and Human Services, Washington, DC (US);
University of Kansas, Lawrence, KS (US);
Northwestern University, Evanston, IL (US);
Abstract
The disclosure provides compounds for reducing the prevalence of the perinucleolar compartment in cells, for example, of formula (I), wherein R, R, R, and Rare as defined herein, that are useful in treating a disease or disorder associated with increased prevalence of the perinucleolar compartment, such as cancer. Also disclosed is a composition containing a pharmaceutically acceptable carrier and at least one compound embodying the principles of the invention, and a method of treating or preventing cancer in a mammal.