This inventor holds 5 USPTO granted patents and 1 published patent application and 1 EPO patent. Top assignee: Arizona State University. Active years: 2016-2022.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Company Filing History:
Years Active: 2016-2022
Title: Innovations by John Spence in Microfluidic Devices
Introduction
John Spence is a notable inventor based in Tempe, AZ (US), recognized for his contributions to the field of microfluidics. He holds a total of 5 patents, showcasing his innovative approach to solving complex problems in crystallography and biological research.
Latest Patents
One of his latest patents is titled "Modular 3-D printed devices for sample delivery and method." This invention features a microfluidic device designed for use in a serial crystallography apparatus. It includes a modular 3D-printed nozzle with an inlet, an outlet, and a first snap engagement feature. Additionally, the device comprises a modular 3D-printed fiber holder that has an outlet and a second snap engagement feature. The design allows for the nozzle and fiber holder to be removably coupled, ensuring that the outlet of the fiber holder aligns with the inlet of the nozzle when engaged.
Another significant patent is "3D printed microfluidic mixers and nozzles for crystallography." This invention presents a hybrid nozzle device that combines a microfluidic mixer with a liquid jet injector. It addresses the challenges of investigating substrate-initiated biological reaction paths using serial crystallography with X-ray free electron lasers (XFELs). The hybrid nozzle enables the injection of aqueous protein crystal jets after rapid mixing, achieving reaction time points suitable for resolving enzyme kinetics.
Career Highlights
John Spence is affiliated with Arizona State University, where he continues to push the boundaries of research in microfluidics and crystallography. His work has significantly impacted the field, providing new tools and methodologies for researchers.
Collaborations
Throughout his career, John has collaborated with esteemed colleagues, including Uwe Weierstall and R Bruce Doak. These partnerships have further enhanced the quality and reach of his innovative work.
Conclusion
John Spence's contributions to the field of microfluidics through his patents and collaborations highlight his role as a leading inventor. His innovative devices are paving the way for advancements in crystallography and biological research.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile