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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10557807 B1

PDFFull Text
Date of Patent:
Feb. 11, 2020

Filed:

May. 22, 2018

3d printed microfluidic mixers and nozzles for crystallography

Applicant:

Arizona Board of Regents on Behalf of Arizona State University, Scottsdale, AZ (US);

Inventors:

Alexandra Ros, Phoenix, AZ (US);

Gerrit Brehm, Göttingen, DE;

Garrett Nelson, Mesa, AZ (US);

John Spence, Tempe, AZ (US);

Uwe Weierstall, Phoenix, AZ (US);

Austin Echelmeier, Tempe, AZ (US);

Assignee:

ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY, Scottsdale, AZ (US);

Attorney:

Michael Best & Friedrich LLP

Primary Examiner:

Taeho Jo

Int. Cl.
CPC ...
G01N 23/2005 (2018.01); B01F 13/00 (2006.01); B33Y 80/00 (2015.01); G01N 23/20025 (2018.01); B01L 3/00 (2006.01);
U.S. Cl.
CPC ...
G01N 23/2005 (2013.01); B01F 13/0062 (2013.01); B01L 3/502715 (2013.01); B33Y 80/00 (2014.12); G01N 23/20025 (2013.01); B01F 2215/0037 (2013.01); B01L 2300/0867 (2013.01); G01N 2223/602 (2013.01);
Abstract

A 3D printed hybrid nozzle device combining a microfluidic mixer with a liquid jet injector that addresses the bottleneck of investigating substrate-initiated biological reaction paths employing serial crystallography with XFELs. The hybrid nozzle provides for injecting aqueous protein crystal jets after fast mixing (<5 ms), reaching reaction time points (e.g., about 10 ms to about 150 ms) suitable to resolve enzyme kinetics.

Find Patent Forward Citations

Ros, Alexandra. (2020). 3d printed microfluidic mixers and nozzles for crystallography (U.S. Patent No. 10557807). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10557807

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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