John Shumaker

Title: John Shumaker: Innovator in Nucleic Acid Sequence Analysis

Introduction

John Shumaker is a notable inventor based in Houston, TX (US), recognized for his contributions to the field of nucleic acid sequence analysis. With a total of 5 patents to his name, Shumaker has made significant advancements in the methodologies used for analyzing polynucleotides.

Latest Patents

One of his latest patents is titled "Parallel primer extension approach to nucleic acid sequence analysis." This innovative method involves analyzing a polynucleotide of interest by providing one or more sets of consecutive oligonucleotide primers that differ within each set by one base at the growing end. The process includes annealing a single strand of the polynucleotide or a fragment of it to the oligonucleotide primers under hybridization conditions. The primers are subjected to single base extension reactions with a polymerase and mutually distinguishable terminating nucleotides. By observing the location and identity of each terminating nucleotide, the sequence or part of the nucleotide sequence of the polynucleotide of interest can be analyzed. Additionally, the patent describes an apparatus that comprises a solid support to which one or more sets of consecutive oligonucleotide primers are attached at defined locations.

Career Highlights

Throughout his career, John Shumaker has worked with esteemed institutions, including Baylor College of Medicine. His work has significantly impacted the field of genetic research and analysis.

Collaborations

Shumaker has collaborated with notable colleagues such as Mitchell D Eggers and Michael E Hogan, contributing to various projects and advancements in his field.

Conclusion

John Shumaker's innovative work in nucleic acid sequence analysis showcases his expertise and dedication to advancing scientific research. His contributions continue to influence the methodologies used in genetic analysis today.