Company Filing History:
Years Active: 2020
Title: Innovations of John S Penn in Hypoxia Detection
Introduction
John S Penn is a notable inventor based in Brentwood, TN (US). He has made significant contributions to the field of medical diagnostics, particularly in the detection of hypoxia. His innovative work has led to the development of a unique compound and method that enhances the ability to identify hypoxic cells and tissues.
Latest Patents
John S Penn holds a patent for a composition and method for detecting hypoxia. This patent includes a compound that features a probe selected from various types of hypoxia-sensitive fluorescence imaging probes. These probes include a hypoxia-sensitive 2-nitroimidazole, a reversible ON-OFF fluorescence imaging probe, and an azo-based fluorescence imaging probe. The method involves contacting cells or tissue with the probe and detecting the fluorescent intensity, where increased intensity indicates hypoxic conditions. Additionally, the patent outlines methods for synthesizing the compound and creating a therapeutic agent that incorporates it.
Career Highlights
John S Penn is affiliated with Vanderbilt University, where he continues to advance research in medical diagnostics. His work is pivotal in improving the understanding and detection of hypoxia, which is crucial for various medical applications.
Collaborations
He has collaborated with notable colleagues, including Imam Uddin and Ashwath Jayagopal, to further enhance the research and development of hypoxia detection methods.
Conclusion
John S Penn's innovative contributions to the field of hypoxia detection exemplify the impact of research and invention in medical diagnostics. His work not only advances scientific knowledge but also holds the potential for significant clinical applications.