Company Filing History:
8 out of 2,611 
1 out of 3 
1 out of 1,132 
Years Active: 1984-2002
Title: **The Innovative Mind of John S. Leigh: Pioneering Advances in Medical Imaging**
Introduction
John S. Leigh, an inventive mind based in Philadelphia, PA, has made significant contributions to the field of medical imaging. With a total of 10 patents to his name, he is at the forefront of developing innovative techniques that enhance our understanding of human anatomy and physiology. His work is characterized by a unique combination of magnetic resonance imaging and electrical impedance tomography.
Latest Patents
Among his most recent patents, Leigh has developed the **Magnetic Resonance-Electrical Impedance Tomography (MREIT)** technique. This groundbreaking method allows for the determination of the local conductivity of an object, which is particularly useful in medical diagnostics. The MREIT technique merges magnetic resonance current density imaging (MRCDI) with electrical impedance tomography (EIT) to capitalize on the strengths of both methodologies. Key steps in this process include the strategic placement of electrodes around a patient, exposure to a strong magnetic field, and the synchronization of MR imaging sequences with current applications through the electrodes. The resulting data not only captures the MR imaging signal but also derives critical information about the internal conductivity of the patient or object being examined.
Additionally, Leigh has pioneered a **Three-Dimensional Localized Proton NMR Spectroscopy** method, achieving acquisition on standard clinical imagers. This innovative approach utilizes a hybrid of chemical shift imaging (CSI) and transverse Hadamard spectroscopic imaging (HSI) to create detailed three-dimensional maps of localized proton spectroscopy within the human brain. The technique has demonstrated a notable gain in sensitivity, providing more accurate imaging results through its advanced approach to signal enhancement.
Career Highlights
John S. Leigh has had illustrious career highlights, primarily collaborating with prestigious institutions such as the **University of Pennsylvania** and the **Trustees of the University of Pennsylvania**. His dedication to advancing medical imaging technology has made a significant impact on both academic circles and clinical practices.
Collaborations
Throughout his career, Leigh has worked alongside esteemed colleagues such as **David A. Roberts** and **Mitchell D. Schnall**. These collaborations have not only enriched his research but have also contributed to the broad spectrum of innovations that emerge from their combined expertise. Their teamwork underscores the importance of collaboration in driving the progress of scientific discovery.
Conclusion
John S. Leigh stands out as a remarkable inventor whose work in medical imaging continues to shape the field. His patented innovations, including the MREIT technique and advanced proton NMR spectroscopy, reflect his commitment to improving diagnostic processes. As he continues to forge new paths in healthcare technology, his legacy as a pioneer in medical imaging remains firmly established.