John Powell

Title: John Powell: Innovator in Antibody Development

Introduction

John Powell is a notable inventor based in Cambridgeshire, GB. He has made significant contributions to the field of biotechnology, particularly in the development of antibodies. With a total of 2 patents to his name, Powell's work focuses on enhancing the stability and efficacy of therapeutic antibodies.

Latest Patents

Powell's latest patents include innovative approaches to antibodies against nerve growth factor (NGF) with enhanced in vivo stability. The present invention provides anti-NGF antibodies that contain an IgG4 constant region comprising a stabilizing hinge region mutation. These antibodies exhibit an unexpectedly long serum half-life in cynomolgus monkeys. Additionally, the patents cover pharmaceutical compositions comprising the anti-NGF antibodies, nucleic acids encoding the NGF antibodies, host cells for expressing the NGF antibodies, and methods of using the antibodies for treating NGF-related diseases or conditions.

Career Highlights

Throughout his career, John Powell has worked with prominent organizations, including Abbott Research B.V. His expertise in antibody development has positioned him as a key figure in the biotechnology sector.

Collaborations

Powell has collaborated with notable professionals in his field, including Duncan Casson and Mark Maginn. These collaborations have further enriched his research and development efforts.

Conclusion

John Powell's contributions to the field of antibody development are significant and impactful. His innovative patents and collaborations highlight his dedication to advancing biotechnology.