Location History:
- Dublin, IE (2015 - 2021)
- Enniskerry, IE (2022)
Company Filing History:
3 out of 136 
1 out of 1 
1 out of 39 
Years Active: 2015-2022
Title: John O'Leary: Innovator in Immunomodulation and Cervical Cytology
Introduction
John O'Leary is a notable inventor based in Dublin, Ireland. He has made significant contributions to the fields of immunomodulation and cervical cytology. With a total of 3 patents, O'Leary's work focuses on innovative methods that have the potential to impact medical treatments and diagnostics.
Latest Patents
O'Leary's latest patents include a method of treatment that relates to immunomodulation. This invention involves an agent that inhibits immunostimulation mediated by a Toll-like receptor, which is useful in treating viral and microbial pathogenesis, diseases involving autoimmunity, inflammation, and cancer. The agent works by antagonizing disulfide bond formation between C98 and C475 of Toll-like receptor 7 (TLR7), thereby preventing TLR7 activation. Additionally, he has developed a method for identifying low-grade cervical cytology cases that are likely to progress to high-grade or cancer. This method utilizes Raman spectroscopy to acquire high-quality spectra from morphologically normal appearing cells, allowing for the differentiation of various grades of cervical pre-cancer with good sensitivities and specificities.
Career Highlights
Throughout his career, O'Leary has worked with esteemed institutions such as the Provost Fellows and Scholars of the College of the Holy and Undivided Trinity of Queen Elizabeth, near Dublin, and the Coombe Lying-in Hospital. His work in these organizations has contributed to advancements in medical research and treatment methodologies.
Collaborations
O'Leary has collaborated with notable individuals in his field, including Luke O'Neill and Sean Daly. These partnerships have fostered a collaborative environment that encourages innovation and the sharing of ideas.
Conclusion
John O'Leary's contributions to immunomodulation and cervical cytology exemplify the impact of innovative thinking in medicine. His patents reflect a commitment to advancing healthcare through research and development. O'Leary's work continues to inspire future innovations in the medical field.