The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 13, 2015

Filed:

Sep. 24, 2009
Applicants:

Luke Anthony O'neill, Dublin, IE;

John O'leary, Dublin, IE;

Sean Daly, Dublin, IE;

Andrea Scharfe Nugent, Dublin, IE;

Inventors:

Luke Anthony O'Neill, Dublin, IE;

John O'Leary, Dublin, IE;

Sean Daly, Dublin, IE;

Andrea Scharfe Nugent, Dublin, IE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/37 (2006.01); A61K 45/06 (2006.01); A61K 39/395 (2006.01); A61K 31/47 (2006.01); A61K 31/00 (2006.01); A61K 31/7088 (2006.01); A61K 38/17 (2006.01); C12N 15/117 (2010.01);
U.S. Cl.
CPC ...
A61K 31/47 (2013.01); A61K 31/00 (2013.01); A61K 31/7088 (2013.01); A61K 38/177 (2013.01); A61K 45/06 (2013.01); C12N 15/117 (2013.01); C12N 2310/17 (2013.01);
Abstract

The invention provides a method for treating or preventing preterm labor in pregnant female subjects. The method comprises the step of administering a therapeutically effective amount of a Toll-like Receptor 9 antagonist sufficient to prevent the activation of Toll-like Receptor 9 by fetal DNA. The invention further provides compositions comprising a Toll-like Receptor 9 antagonist for use in the methods of the invention. The compositions and methods of the present invention enhance gestation and therefore improve neonatal morbidity and mortality.


Find Patent Forward Citations

Loading…