The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 17, 2021

Filed:

Dec. 20, 2017
Applicants:

Technological University Dublin, Dublin, IE;

The Provost, Fellows, Foundation Scholars, and the Other Members of the Board, of the College of the Holy and Undivided Trinity of Queen Elizabeth Near Dublin, Dublin, IE;

Inventors:

Shiyamala Duraipandian, Dublin, IE;

Fiona Lyng, Dublin, IE;

Damien Traynor, Dublin, IE;

John O'Leary, Dublin, IE;

Cara Martin, Dublin, IE;

Padraig Kearney, Dublin, IE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 21/65 (2006.01); G01J 3/44 (2006.01); G01N 33/543 (2006.01); G01N 33/574 (2006.01);
U.S. Cl.
CPC ...
G01N 21/65 (2013.01); G01J 3/44 (2013.01); G01N 33/54373 (2013.01); G01N 33/57411 (2013.01);
Abstract

The present invention provides a method of using Raman spectroscopy for identification of low grade cervical cytology cases likely to progress to high grade/cancer. The Applicant has found that high quality Raman spectra can be successfully acquired from morphologically normal appearing cells from negative, LSIL and HSIL Thinprep® specimens and different grades of cervical pre-cancer can be separated with good sensitivities and specificities. Raman spectroscopy can further identify different categories of the LSIL cases i.e., whether they are likely to regress to negative or progress to HSIL cytology.


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