Vaudreuil, Canada

John Mancuso

USPTO Granted Patents = 3 



Average Co-Inventor Count = 9.3

ph-index = 1

Forward Citations = 10(Granted Patents)


Location History:

  • Sherbrooke, CA (2014)
  • Vaudreuil, CA (2013 - 2015)

Company Filing History:


Years Active: 2013-2015

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3 patents (USPTO):Explore Patents

Title: The Innovative Contributions of John Mancuso

Introduction

John Mancuso is a distinguished inventor based in Vaudreuil, Canada, renowned for his contributions to the field of biochemistry. With a total of three patents to his name, Mancuso has made significant strides in the development of compounds that target histone deacetylase, a key enzyme involved in various cellular processes and diseases.

Latest Patents

Mancuso's latest inventions include two notable patents that focus on histone deacetylase (HDAC) inhibition. The first, titled "Dibenzo[b,f][1,4]oxazepin-11-yl-N-hydroxybenzamides as HDAC inhibitors," relates to compounds designed specifically for the inhibition of HDAC. This invention details compounds of formula (I), where Q, J, L, and Z are defined within the specification.

Another important patent, "Inhibitors of histone deacetylase," describes both compounds and methods aimed at inhibiting HDAC enzymatic activity. Similarly, it provides for compounds of formula (I), N-oxides, hydrates, solvates, pharmaceutically acceptable salts, prodrugs, complexes, and various mixtures and isomers, offering a comprehensive approach to targeting this essential enzyme.

Career Highlights

Throughout his career, John Mancuso has been associated with prominent companies in the pharmaceutical sector. Notably, he has contributed his expertise at Methylgene, Inc. and Envivo Pharmaceuticals, Inc. His work in these organizations has paved the way for advancements in drug development centered around HDAC inhibition.

Collaborations

In his innovative journey, Mancuso has collaborated with esteemed colleagues such as Pierre Tessier and David Smil. These partnerships highlight the collaborative nature of scientific research, bringing together diverse expertise to propel their work forward.

Conclusion

John Mancuso's contributions to the field of biochemistry, particularly in the development of HDAC inhibitors, demonstrate the impact of dedicated inventors in advancing medical science. His patents not only showcase his innovative spirit but also reflect the importance of collaboration in achieving groundbreaking results in pharmaceutical research.

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