The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 18, 2014

Filed:

Nov. 03, 2008
Applicants:

Tammy Mallais, Kirkland, CA;

Oscar Moradei, Kirkland, CA;

Alain Ajamian, Montreal, CA;

Pierre Tessier, Hawkesbury, CA;

David Smil, Montreal, CA;

Sylvie Frechette, Verdun, CA;

Silvana Leit, Kirkland, CA;

Patrick Beaulieu, Laval, CA;

Robert Deziel, Mount-Royal, CA;

John Mancuso, Sherbrooke, CA;

Inventors:

Tammy Mallais, Kirkland, CA;

Oscar Moradei, Kirkland, CA;

Alain Ajamian, Montreal, CA;

Pierre Tessier, Hawkesbury, CA;

David Smil, Montreal, CA;

Sylvie Frechette, Verdun, CA;

Silvana Leit, Kirkland, CA;

Patrick Beaulieu, Laval, CA;

Robert Deziel, Mount-Royal, CA;

John Mancuso, Sherbrooke, CA;

Assignee:

MethylGene Inc., Montreal, CA;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/5377 (2006.01); C07D 413/02 (2006.01); A61K 31/4535 (2006.01); C07D 417/02 (2006.01); C07D 211/02 (2006.01); C07D 401/02 (2006.01); C07D 401/14 (2006.01); A61K 31/426 (2006.01); A61K 31/421 (2006.01); A61K 31/415 (2006.01); A61K 31/40 (2006.01); A61K 31/381 (2006.01); C07D 277/20 (2006.01); C07D 263/30 (2006.01); C07D 231/10 (2006.01); C07D 333/02 (2006.01);
U.S. Cl.
CPC ...
Abstract

This invention relates to compounds and methods for the inhibition of HDAC enzymatic activity. More particularly, the invention provides for compounds of formula (I), (I) and N-oxides, hydrates, solvates, pharmaceutically acceptable salts, prodrugs and complexes thereof, and racemic and scalemic mixtures, diastereomers and enantiomers thereof, wherein L, M, n, R, W, X and Y are as defined in the specification.


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