Location History:
- Framingham, MA (US) (1989 - 1992)
- Cambridge, MA (US) (1994 - 2001)
- Charlestown, MA (US) (2014 - 2017)
- Brighton, MA (US) (2017)
Company Filing History:
24 out of 2,961 
7 out of 2,882 
1 out of 1,206 
Years Active: 1989-2024
Title: The Innovative Contributions of John J. Mekalanos in the Field of Biotechnology
Introduction: John J. Mekalanos is a prominent figure in the field of biotechnology, known for his significant contributions and innovations. Based in Cambridge, MA, he holds an impressive portfolio with 26 patents to his name. His work primarily focuses on the regulatory mechanisms of human proteins and novel methods for utilizing polypeptides in medical applications.
Latest Patents: Among his latest patents is the invention titled "Human CGAS-DNA complex and encoded protein." This invention highlights the discovery of the human-specific regulatory control of cGAS and details the structure of the active human cGAS-DNA complex. Additionally, it includes compositions comprising modified hcGAS polypeptides, hcGAS-DNA complexes, and methods of screening for modulators of these complexes' structure, expression, and activity. Another significant patent is focused on "Methods for displaying polypeptides and uses thereof," which provides innovative methods and compositions for displaying a polypeptide on a tubular structure, with applications in the production of antibodies or vaccines.
Career Highlights: John J. Mekalanos has held key positions in several prestigious institutions, notably serving with the President and Fellows of Harvard College and The General Hospital Corporation. His roles in these organizations have allowed him to lead groundbreaking research initiatives and facilitate advances in the understanding of microbiology and immunology.
Collaborations: Throughout his career, Mekalanos has collaborated with esteemed colleagues including Samuel I. Miller, III, and Andrew Camilli. These collaborations have significantly enriched his research endeavors and have played a crucial role in the advancement of his innovative projects.
Conclusion: John J. Mekalanos exemplifies the spirit of innovation in biotechnology through his extensive patent portfolio and collaborative efforts. His inventions continue to push the boundaries of scientific knowledge and have the potential to lead to substantial advancements in medical treatments and therapeutic strategies.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.