John J Lauff

Title: The Innovations of John J. Lauff

Introduction

John J. Lauff is a notable inventor based in Rochester, NY (US). He has made significant contributions to the field of microbial production, particularly in the synthesis of indigo. With a total of 5 patents to his name, Lauff's work exemplifies the intersection of biology and chemistry in innovative processes.

Latest Patents

One of Lauff's latest patents focuses on the microbial production of indigo. This patent presents an improved process for the biosynthetic production of indigo, emphasizing the removal of unwanted by-products such as isatin or indirubin from the production broth. The process involves enzymatic activity using an isatin-removing enzyme, such as isatin hydrolase, or other techniques like adjusting process parameters (elevated temperature, pH). Additionally, the broth can be treated with appropriate adsorption compounds, such as carbon or specific resins, to enhance the purity of the indigo produced. By removing isatin, which is a precursor to indirubin, the levels of indirubin are effectively decreased, leading to a more efficient production process.

Career Highlights

Throughout his career, John J. Lauff has worked with various companies, including Genencor International, Inc. His experience in these organizations has contributed to his expertise in the field of microbial processes and biotechnology.

Collaborations

Lauff has collaborated with notable individuals in his field, including Walter Weyler and Timothy C. Dodge. These collaborations have likely enriched his research and development efforts, fostering innovation in his projects.

Conclusion

John J. Lauff's contributions to the field of microbial production, particularly in the synthesis of indigo, highlight his innovative spirit and dedication to advancing biotechnology. His patents and collaborations reflect a commitment to improving industrial processes through scientific research.