John H Kepler

Title: Innovations by John H. Kepler

Introduction

John H. Kepler is an accomplished inventor based in Lexington, MA (US). He holds three patents that showcase his expertise in allergen detection technologies. His work has significantly contributed to advancements in food safety and allergen management.

Latest Patents

One of his latest patents is titled "Systems and methods for allergen detection." This invention provides systems, devices, signaling polynucleotides (SPNs), detection agents, and methods for detecting the presence and/or absence of one or more allergens in a sample, particularly a food sample. The detection system includes a separate sampler, at least one disposable detection vessel for receiving and processing a test sample, and a detection device for measuring a fluorescent signal. SPNs derived from aptamers that bind allergens are provided as detection agents. These SPNs have a single open structure and are labeled with a fluorophore. Changes in fluorescence polarization of SPNs upon the binding of allergens are measured to calculate the allergen content in a sample.

Another notable patent is the "Portable allergen detection system." This invention provides systems, devices, and methods for detecting the presence and/or absence of one or more allergens in a sample, particularly a food sample. The detection system includes a separate sample pickup, one or more disposables for receiving and processing a test sample, and a detection device that can execute allergen detection testing in minutes. The present detection system and device are compact and portable, making them highly efficient for real-time allergen testing.

Career Highlights

Throughout his career, John H. Kepler has worked with various companies, including Dots Technology Corp. and Helicos Biosciences Corporation. His contributions to these organizations have been instrumental in developing innovative solutions in the field of allergen detection.

Collaborations

John has collaborated with notable individuals such as Adi Gilboa-Geffen and Renuka Babu Brown. These partnerships have further enhanced his research and development efforts in allergen detection technologies.

Conclusion

John H. Kepler's innovative work in allergen detection has made a significant impact on food safety. His patents reflect his commitment to advancing technology in this critical area.