Company Filing History:
Years Active: 1998-2017
Title: John Graham Oakeshott: Innovator in Enzyme Technology
Introduction
John Graham Oakeshott is a prominent inventor based in Wanniassa, Australia. He has made significant contributions to the field of enzyme technology, particularly in the degradation of organophosphates. With a total of 9 patents to his name, Oakeshott's work has implications for environmental remediation and agricultural practices.
Latest Patents
Oakeshott's latest patents include groundbreaking inventions such as enzymes for degrading organophosphates. This invention focuses on enzymes capable of hydrolyzing organophosphate (OP) molecules, specifically variants of the OpdA enzyme that exhibit improved activity compared to the naturally occurring OpdA. Additionally, he has developed polypeptides that possess organophosphate hydrolyzing activity for pesticides like chlorpyrifos methyl, diazinon, and parathion ethyl. Another notable patent involves phosphotriesterase from Agrobacterium radiobacter P230, which provides enzymes capable of hydrolyzing OP molecules. This invention includes a phosphotriesterase enzyme identified from a strain isolated from soil that hydrolyzes OP pesticides, along with the gene encoding that enzyme. Furthermore, it offers mutants of the identified phosphotriesterase enzyme with altered substrate specificity, highlighting the potential use of these enzymes in bioremediation strategies.
Career Highlights
Oakeshott is affiliated with the Commonwealth Scientific and Industrial Research Organisation, where he continues to advance research in enzyme technology. His work has garnered attention for its innovative approach to addressing environmental challenges posed by harmful pesticides.
Collaborations
Throughout his career, Oakeshott has collaborated with notable colleagues, including Robyn Joyce Russell and Richard David Newcomb. These partnerships have contributed to the success and impact of his research.
Conclusion
John Graham Oakeshott stands out as a key figure in the field of enzyme technology, with a focus on developing solutions for environmental issues related to organophosphates. His innovative patents and collaborations reflect his commitment to advancing scientific knowledge and practical applications in this important area.